b'uFromPage 45The panel said it has not yet made an official rec- 2. dilute bleach baths, ommendation for topical calcineurin inhibitors (TCIs)3. dietary avoidance/elimination, andtopicalcorticosteroids(TCS)vs.ruxolitinib,4. allergen immunotherapy, and explaining that many clinical experts and patients5.systemic treatments (biologics/will start with TCS or TCI first. Similarly, clinicalmonoclonal antibodies, small molecule experts expressed that although most patients may notimmunosuppressants [cyclosporine, prefer ruxolitinib as first-line treatment, it might be amethotrexate, azathioprine, mycophenolate, resource to consider for those patients for whom TCSJAK inhibitors], and systemic corticosteroids) and TCI do not yield sufficient control. and UV phototherapy (light therapy).Guidance addressing atopic dermatitis (AD) man- 1Liu J, Desai K, Then C-C, Sturm, D. Atopic Dermatitis Treatments agement, last was issued in 2012 by the two specialtyBefore and After Initiation of Ruxolitinib Cream: Analysis of a US groups.Thepanelagreedon25recommendationsPayer Claims Database.Presented at the American Academy of Der-to gain and maintain control of AD for patients withmatology (AAD) Annual Meeting, San Diego, CA, March 8-12, 2024.mild, moderate, and severe AD.2AAAAI/ACAAI JTF Atopic Dermatitis Guideline Panel; Chu DK, In addition to topical JAK inhibitors, the documentSchneider L, Asiniwasis RN, Boguniewicz M, et. Al. Atopic dermati-tis (eczema) guidelines: 2023 American Academy of Allergy, Asthma advises on optimal use of:and Immunology/American College of Allergy, Asthma and Immunol-1. topical treatments (barrier moisturizationogy Joint Task Force on Practice Parameters GRADE- and Institutedevices, corticosteroids, calcineurin inhibitors,of Medicine-based recommendations. Ann Allergy Asthma Immunol. 2024 Mar;132(3):274-312. doi: 10.1016/j.anai.2023.11.009. Epub PDE4 inhibitors [crisaborole], occlusive [wet2023 Dec 18. PMID: 38108679.wrap] therapy, adjunctive antimicrobials, application frequency, maintenance therapy),Topical Treatment Pattern for AD Before and After Ruxolitinib Cream UseSource: Atopic Dermatitis Treatments Before and After Initiation of Ruxolitinib Cream: Analysis of a US Payer Claims Database.Presented at the American Academy of Dermatology (AAD) Annual Meeting, San Diego, CA, March 8-12, 2024.46'