b'u From Page 71Forexample,anhedonia,impulsiv-ityandsubstanceuseareassociated Indeed, there is the possibility of symptom with suicidal behavior and have also beenassociatedwithlesslikelihoodexacerbation in patients with a history of adopting COVID-19 precautionaryof suicide attempt who test positive for behaviors such as physical distancing, wearing mask, or handwashing. COVID-19 since postmortem examination of The authors suggested that the asso-ciation of history of suicide attemptsbrains of individuals diagnosed with severe withCOVID-19positivityintheCOVID-19 infection revealed COVID-19- younger and obese subgroups also is worthmorediscussion.Forexam- related impaired brain neurotransmission. ple,suicideriskinschizophreniais highestforyoungadultsbutlowestStudy teamfor patients older than 65 years, and although BMI has not been associated with suicide risk in schizophrenia or schizoaffective disorder, obesity is associated withTheresearchersalsopointedtorecentresearch higherlevelsofimmunesystemdysregulationassociatingprimaryhumoralimmunodeficiencies andinflammationinpatientswithschizophrenia.withpsychiatricdisorders(includingschizophre-Relatedly,markersofimmunedysregulationandnia) and suicide attempts in the same cohort. It inflammation in the periphery and central nervousis,thereforeconceivable,althoughspeculative, system are elevated in suicide attempters relative tothat the association of suicide attempt history with nonattempters, they noted. COVID-19mightreflectdysregulatedimmune Source: History of Suicide Attempts and COVID-19 Infection in Veterans with Schizophrenia or Schizoaffective Disorder: Moderating Effects of Age and Body Mass Index; Complex Psychiatry; www.ncbi.nlm.nih.gov/pmc/articles/PMC8805065/80'