One of the most commonly used medication classes worldwide, proton pump inhibitors (PPIs) are effective for treating acid-related stomach disorders, such as ulcers, heartburn or acid reflux.
Prescription Medications Affect Survival Rates in Metastatic Prostate Cancer
How do prescription medications affect overall survival in metastatic hormone-sensitive prostate cancer?
Hepatocellular Carcinoma Screening Associated With Improved Survival in Patients Cured of HCV Infection
Hepatitis C virus (HCV) is the most common blood-borne pathogen in the United States, with HCV-related cirrhosis being the leading cause of primary liver cancer, or hepatocellular carcinoma (HCC).
Study: Propofol Use Should Be Minimized in Children With ALL
A study involving military researchers has raised concerns about the use of certain types of anesthesia in children with acute lymphocytic leukemia (ALL)
Circumstances Linked to Bleeding Risk With Chronic Liver Disease Diagnosis
A recent study looked at risk factors for non-variceal bleeding within the first year after diagnosis of chronic liver disease in veterans.
Multiple Myeloma Patients Have Longer Survival With Military Healthcare
MHS beneficiaries with multiple myeloma (MM) had improved overall survival compared to MM patients from the U.S. general population, according to a new report.
Gastrointestinal Symptoms Frequently Diagnosed in Deployed Gulf War Veterans
Deployed Gulf War veterans frequently developed several gastrointestinal symptoms, including irritable bowel syndrome, dyspepsia, diarrhea, bloating and constipation, and those often persisted long after returning home, according to a new study.
Use of Non-therapeutic Laparotomy Decreased in Recent Wars but Remain Essential Battlefield Trauma-Care Tool
As combat casualty care improved over time during the wars in Iraq and Afghanistan, the use of nontherapeutic laparotomy (NTL) decreased.
Study: Eating Processed, Red Meat Raises the Risk of Type 2 Diabetes
Consuming meat, especially processed and red meat, is a risk factor for the development of type 2 diabetes, according to a new study involving VA researchers.
Misdiagnosis of Community-Acquired Pneumonia Occurs More Than Half the Time at VA Hospitals
Pneumonia diagnoses change more often than not at VA hospitals, either because a veteran initially thought to have the infection is diagnosed with something else or because the community-acquired pneumonia diagnosis was missed when the patient entered the hospital.
Persian Gulf War Service Linked to High Rates of Myeloproliferative Neoplasms
A study of almost a half-million veterans has found for the first time a link between environmental exposures during military service and the development of myeloproliferative neoplasms (MPNs).
Removing Race From Lung-Function Equations Shifts Disease Classifications
In 2023, the American Thoracic Society recommended race-neutral interpretation of lung function and requested the investigation of “consequences for the yet-unquantified number of individuals with results near decision-making thresholds.”
Anti-TNF Agents Associated With Kidney Function Decline in IBD Patients
The introduction of biologic therapies, such as antitumor necrosis factor (TNF) agents, has revolutionized the management of inflammatory bowel disease (IBD)—a group of diseases characterized by chronic inflammation of the gastrointestinal tract.
Cytomegalovirus Examined in Breast Cancer Tumor Development
Cytomegalovirus (CMV), a herpesvirus that leads to lifelong infection, appears to play some role in breast cancer, according to a new study.
Why Do Surprising Distant Metastases Occur in 10-30% of ‘Cured’ Breast Cancer
PITTSBURGH — In most cases of breast cancer, no evidence of spread is found, the primary tumor is removed and the patient is as close to cured as possible, at that point. In 10% to 30% of cases in women, however, distant metastases recur after years to decades. “This...
New Efforts Seek to Reduce Treatment Time, Travel for Breast Cancer Patients
WASHINGTON — Earlier this year, the VA announced expansion of the "Close to Me" cancer program, with the understanding that access to medical centers providing specialty cancer care can be difficult for many veterans. The expansion will bring new cancer diagnosis,...
VHA Closely Follows Clinical Guidelines on Gender-Affirming Hormone Therapy
When initiating gender-affirming hormone therapy (GAHT) at the VHA, clinicians achieved high overall concordance between current GAHT initiation practices and guidelines, particularly for feminizing GAHT, according to a recent study.
Strong Links Found Between Obstructive Respiratory Disease in Veterans, Psychiatric Health Conditions
Veterans with obstructive respiratory disease should receive timely screening and treatment for comorbid psychiatric and medical conditions that frequently accompany the condition, according to a new study.
COVID-19 More Severe in Veterans With Chronic Lung Diseases
Veterans with chronic lung diseases, particularly idiopathic pulmonary fibrosis (IPF), other interstitial lung diseases (ILD) and chronic obstructive pulmonary disease (COPD), have an increased risk of experiencing more severe 30-day outcomes with COVID-19, according to a recent study.
Are PSA Values Reliable in Transgender Women to Detect Prostate Cancer?
In a VHA population, prostate-specific antigen (PSA) values in more than one-third of transgender women receiving estrogen were found to be undetectable, which indicates that PSA values in transgender women should be interpreted cautiously, according to a recent study.
Using Spironolactone to Treat HFpEG Reduced All-Caused Death
For veterans with heart failure with preserved ejection fraction (HFpEF), spironolactone use reduced all-cause death and demonstrated a favorable trend in reducing hospitalizations, according to a study of a real-world national cohort of patients with HFpEF.
Novel Psychotherapy Targeting Unresolved Trauma Reduces Chronic Pain in Older Adults Better Than Traditional CBT
Chronic pain in older adults can be significantly reduced using a newly developed psychotherapy called emotional awareness and expression therapy (EAET), which confronts past trauma and stress-related emotions that can exacerbate pain symptoms, according to a new study.
Shared Decision-Making Tool Promotes More Effective Use of Lung Cancer Screening
Research, including a new study of 57,000 U.S. veterans diagnosed with lung cancer, has shown that low-dose computed tomography lung cancer screening (LCS) saves lives.
Tracking Genetic Risk to Better Understand Which Veterans Have Alzheimer’s
Because of overlapping symptom profiles observed in cognitive disorders, psychiatric disorders, and environmental exposures such as head injury, clinicians can find it difficult to detect early signs of Alzheimer’s disease and related dementias (ADRD).
Pathogenic Variants Found in More Nonbladder Urinary Tract Cancer Patients
In an effort to evaluate factors that could affect the likelihood of identifying a clinically actionable germline pathogenic variant (PV), a new study investigated a real-world multicenter cohort of patients with urinary tract cancer (UTC).
Novel Genetic Associations Identified in So-Called Macular Pucker
Symptoms of epiretinal member (MRM), sometimes called macular pucker, can be severe and require surgery. Patients often complain of loss of central vision and/or visual distortion (i.e. metamorphopsia or “wavy vision”).
Agent Orange Exposure Not Linked to Hepatocellular Carcinoma
U.S. veterans are much more likely to be diagnosed with hepatocellular carcinoma, but at least one toxic exposure during military service doesn’t appear to have much to do with that.
GAO: Servicemembers in Need of Mental Health Services Are Falling Through the Cracks as They Transition to VA Care
Two recent investigations by the Government Accountability Office (GAO) have highlighted how seemingly small procedural issues and technical errors can lead to servicemembers and veterans not receiving much-needed mental health services.
Mohs Surgery at NY Harbor VAMC Reduced Reexcision, Rerepair Needs
Mohs micrographic surgery (MMS) is the standard of care for treating certain types of keratinocyte carcinoma (KCs), but it has not been uniformly accessible to veterans treated by the VHA, according to a recent research letter.
Study: High-Frequency Ultrasound Better as Supplementary Tool for Tumor ID
High-frequency ultrasound (HFUS) can safely and efficiently visualize cutaneous tumor characteristics including depth, but how accurate is it?
