While clinical trials are essential for advancing treatment options in oncology and making certain patients receive innovative care, too few cancer patients are referred to them, according to a new study.
Care Access Doesn’t Explain Racial Disparities in Rectal Cancer
Does differential access to care explain racial disparities in treatment and outcomes of rectal cancer? A new study from the Uniformed Services University of the Health Sciences suggested that other factors are likely to be at play.
Pandemic Decreased Already Too Low Lung Cancer Screening Rates
A new study demonstrated how critically the COVID-19 pandemic affected lung cancer screening (LCS).
More Point-of-Care Testing in Military Could Help Curb STI Transmissions
Sexually transmitted infections (STIs) affect an estimated 1 in 5 servicemembers, making early diagnosis and treatment important for controlling their spread among this high-risk population.
New Study Warns About Increased Antibiotic Resistance Against Third-Generation Broad-Spectrum Antibiotics in VA Facilities
VHA facilities across the United States have experienced a concerning rise in antibiotic resistance to third-generation cephalosporins, a class of broad-spectrum antibiotics commonly used to treat the Enterobacterales bacterial species.
Indeterminate Liver Nodules Have a High but Variable Risk of HCC
For more than a decade, the Liver Imaging Reporting and Data System (LI-RADS) has been used to standardize the interpretation and reporting of liver lesions in patients at high risk for hepatocellular carcinoma (HCC).
Homelessness Substantially Increases Risk of Death in Veterans With CKD
U.S. veterans with a history of homelessness had a much greater risk of end-stage kidney disease (ESKD) and death, according to a new study, underscoring the role of housing as a social determinant of health.
Faulty Cell Function in Gulf War Illness Likely Caused By Exposure to Hazardous Agents
Veterans suffering from Gulf War illness (GWI), also known as Gulf War Syndrome (GWS), have faulty cell function that is likely caused by intense exposure to hazardous biological and chemical agents during war service, according to a new study.
GLP-1 RAs Promising for Reducing Cirrhosis, Mortality in Liver Disease Patients
Treatment with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) showed promise in lowering the incidence of cirrhosis and mortality in veterans with metabolic dysfunction-associated steatotic liver disease (MASLD) and diabetes, as long as the drug was initiated early in the course of the disease.
Surveys: Better HCC Surveillance Seen as Key to Improved Survival Rates
PALO ALTO, CA — Recent surveys found important gaps in knowledge and perceived barriers to hepatocellular carcinoma (HCC) surveillance in cirrhosis patients in the United States, especially with primary care providers. Even though hepatocellular carcinoma (HCC)...
Early Dialysis Leads to Modest Gains in Life Expectancy, Less Home Time
Older adults with reduced kidney function who start dialysis within 30 days and aren’t referred for transplant have modest gains in life expectancy and less time at home, according to a recent study.
Understanding Bispecific Antibodies for B-Cell Lymphoma Treatment
Bispecific antibodies represent a new approach to cancer immunotherapy that offers a two-for-one mechanism of action to increase efficacy in treating several types of lymphoma and multiple myeloma and other hematologic malignancies.
Cholesterol Medication Ezetimibe Promising for Lowering Alzheimer’s Disease Risk
The mechanism through which heart disease elevates the risk of Alzheimer’s disease and related dementia (ADRD) has been investigated intensively.
What Is the Role of the X Chromosome in Alzheimer’s Disease Genetics?
The X chromosome makes up 5% of the human genome and carries a high proportion of genes expressed in the brain. Yet, it is a relatively unexplored as a potential source of genetic variation in AD, according to a new study.
How PTSD, Cognitive Decline Affect Veterans’ Alzheimer’s Disease Biomarkers
While post-traumatic stress disorder (PTSD) and subjective cognitive decline (SCD) are independent risk factors for Alzheimer’s disease (AD) and dementia, the association of their interaction on AD biomarkers has not been clear.
Breaking Barriers in Kidney Care: Cynthia Delgado’s Pioneering Efforts Lead to More Equitable Transplantation Practices at the VA
For more than two decades, the calculation of estimated glomerular filtration rate (eGFR) — a critical measure of kidney function — included race as a variable.
Black Americans Have Less Alzheimer’s Disease Awareness, Despite Higher Risk
Older Black Americans are almost twice as likely as white Americans to be affected by Alzheimer’s and related dementias, with 21.3% of Black Americans aged 70 and older living with the disease.
Traumatic Brain Injury Linked to Much Higher Risk of Arrhythmia in Veterans
Traumatic brain injury, especially involving penetration, significantly increased the risk for atrial fibrillation or atrial flutter in U.S. military servicemembers and veterans, according to a new study.
Military Service, Race Make Black Veterans More Likely To Have Metastatic Prostate Cancer
The issue of metastasis in prostate cancer can’t really be discussed without a startling fact: Black men are disproportionately affected by prostate cancer (PCa), with earlier presentation, more aggressive disease, and higher mortality rates vs. white men.
VA Continues Research on Radioligands to Optimize Treatment of mCRPC
The promising outcomes from studies of the radioligand lutetium Lu 177 vipivotide tetraxetan (Lu177-PSMA) as a second-line therapy for metastatic castration-resistant prostate cancer (mCRPC) has encouraged researchers to explore its effectiveness when moved earlier in treatment and in combination with other cancer therapies.
Veterans’ Higher Risk of Metastatic Prostate Cancer Drives Continuous Treatment Updates at VA
The U.S. government and the VA increasingly recognize the increased risk of prostate cancer faced by veterans and its relationship to service in areas of conflict.
Consensus Statement, Real-World Experience Guide Lu177-PSMA Use
Since receiving Food and Drug Administration (FDA) approval in 2022 for use in metastatic castration-resistant prostate cancer (mCRPC), adoption of lutetium Lu 177 vipivotide tetraxetan (Lu177-PSMA) has grown rapidly.
Treatment for mCRPC Undergoes Constant Reassessment, Improvement at VA
As the options for treatment of metastatic castration-resistant prostate cancer (mCRPC) continues to increase, determining the best order for sequencing them becomes more complicated.
Review Finds Little Evidence That Massage Therapy Relieves Painful Health Conditions
For individuals seeking relief from painful health conditions, there’s low certainty of evidence that massage therapy will ease their pain, according to a recent review article.
New Algorithm Developed for Urinary Retention Evaluation, Catheterization
A new algorithm could improve care for adult inpatients who need to be evaluated for urinary retention and possible catheterization, according to a recent study.
Unraveling the Mystery of Long COVID: VA Steps Up for Nation in Crisis
By March 2020, the SARS-COV-2 virus had reached every inhabited continent on the globe, with devastating impact. In response, the U.S. and many other countries entered lockdowns to slow the spread and reduce deaths from the virus.
Innovative Pain Self-Management Program Improved Pain, Depressive Symptoms in HIV Patients
For almost three decades, antiretroviral therapy (ART) has enabled people with HIV to have nearly normal life expectancies. But as many as 85% of them experience chronic pain, due in part to common medical comorbidities and the side effects of life-saving treatments.
Microvascular Complications of Type 2 Diabetes Drop When PTSD Resolves in Veterans
Post-traumatic stress disorder (PTSD) has a range of adverse effects in veterans, and about 7% are affected at some point in their lifetimes. A recent study puts a spotlight on an unexpected co-morbidity—worsening Type 2 diabetes (T2D) outcomes.
Alternative Prostate Cancer Screening Guidelines for U.S. Black Men
In the United States, Black men are at highest risk for being diagnosed with and dying from prostate cancer.
Review Authors Urge More Genetic Testing of BRCA for Male Cancer Patients
Even though half of all carriers of inherited cancer-predisposing variants in BRCA1 and BRCA2 are male, the implications for their health tend to be under-recognized compared to females, according to a new study.