Can genetic scores provide an objective measure of prostate cancer risk and aid screening decisions?
Vaccinations Can Help Prevent Flu, COVID-19 Co-Infection
While co-infection with more than one respiratory virus was especially a problem this fall and winter, it has happened before, especially in an environment where SARS-CoV-2 is circulating.
VHA Data Supports Routine Pneumococcal Conjugate Vaccination in Older Adults
As part of the continual evolution of pneumococcal vaccination recommendations, guidelines recently have been updated to urge more use of pneumococcal conjugate vaccines in older adults.
Study Examines Reasons for Vaccine Hesitancy in Patients With IBD
Even after years of the COVID-19 pandemic, data remains somewhat limited on the safety profile of SARS-CoV-2 vaccine in patients taking immunosuppressive medications.
MGUS-MM Progression Differs Between African Americans, Caucasians
While it is widely known that African Americans (AA) are at higher risk for multiple myeloma (MM), precisely what factors create the disparity are not well understood.
Walter Reed, NIAID Scientists Help Develop Monoclonal Antibodies That Might Block Epstein-Barr Virus Infection; EBV Linked to MS Development
Scientists at the National Institute of Allergy and Infectious Diseases (NIAID) and Walter Reed Army Institute of Research (WRAIR) have developed a panel of investigational monoclonal antibodies (mAbs) that target two key proteins—gH and gL—on the surface of the Epstein-Barr virus (EBV).
COVID-19 Reinfection Adds Significant Risk to Multiple Organ Systems
Despite misconceptions that prior COVID-19 infections can keep patients from having severe cases in the future, a new study suggests that recurrent cases pile on the risk of adverse health conditions in multiple organ systems.
Head and Neck Cancer Driven by HPV Has Distinct Genetic, Immune Variants
Most new diagnoses of oropharyngeal cancer, a type of head and neck cancer, are driven by human papillomavirus (HPV) infections, with distinct genetic and immune differences in HPV-driven and non-HPV-driven head and neck cancer, according to a new study.
Pandemic Brought About Significant Changes in Orthopedic Injuries
Much of the focus during the COVID-19 pandemic has been on the infection itself, as well as persistent symptoms. But many other aspects of healthcare underwent changes of SARS-CoV-2 and the efforts to combat it.
Similar Cardiovascular Outcomes Found in Veterans Treated With Two Common Blood Pressure Medications — Chlorthalidone and Hydrochlorothiazide
In “surprising” results, two common diuretics used to control blood pressure, chlorthalidone and hydrochlorothiazide, had no differences in outcomes for cardiovascular events, including death, in veteran patients, according to a new study.
Factors Linked to Severe COVID-19 Among Vaccinated, Hospitalized Veterans
Although vaccination and boosting remain the best defense against COVID-19, breakthrough infections among those vaccinated and boosted are exceedingly common.
Large VA Study Finds Lower Prostate Cancer Screening Rates Associated With Subsequent Increases in Metastatic Cancer
Aside from skin cancer, prostate cancer is the most common cancer among male veterans. When diagnosed at an early stage, prostate cancer is highly curable.
VHA Mental Health Staffing Levels Affect Suicide-Related Events in Veterans
VHA facilities appear to have limited staff who can provide mental health care services, and increasing mental health staffing could reduce suicide-related events in veterans, according to a new study.
Polypharmacy Associated With Worse Outcomes in Veterans With HIV
The good news, according to a recent study, is that medical intensive care unit (MICU) admissions have been declining in people with HIV infection (PWH).
Degree of Diastolic Dysfunction Similar With and Without HIV
Human immunodeficiency virus (HIV) infection is known to be associated with subclinical cardiomyopathy, diastolic dysfunction and increased risk of cardiovascular death.
HIV Prevention Use Remains Too Low in U.S. Military
Even though about 20.9% of U.S. servicemembers report a high risk of HIV infection, only about 2,000 of them had accessed HIV pre-exposure prophylaxis (PrEP), as of 2017.
SCT-Related Deaths Might Be Underestimated in U.S. Military
Sickle cell trait (SCT), a condition in which a person has one abnormal allele of the hemoglobin beta gene, affects an estimated 5.02% of non-Hispanic blacks, 1.08% of Hispanics and 0.1% of whites in the U.S. military.
Achieving Treatment-Free Remission in CML: Best Approaches, Best Candidates
In less than two decades, the advent of targeted therapies transformed chronic myeloid leukemia (CML) from a death sentence with a five-year survival rate of just 22% to a chronic condition with five-year survival exceeding 90%.
Severe COVID-19 Illness Low for Veterans After Vaccination Plus Booster
Veteran patients who received a COVID-19 vaccination series, plus a booster vaccine dose, had a low incidence of hospitalization, death or severe illness from COVID-19, according to a new study.
VA Underused Pharmacotherapies for COVID-19 When First Authorized
When antiviral agents and monoclonal antibodies were first authorized for use at the beginning of the year, few of them were prescribed at the VA, according to a new study.
Veterans With Service-Linked Disabilities Fare Worse After TKA
Service connection (SC) status appears to worsen outcomes for veterans receiving total knee-arthroplasty, according to a new report.
Veterans With RA Face Higher Mortality Risks Than Those Without
Although lessening over time, patients with rheumatoid arthritis (RA) in the VHA have higher risk of all-cause and cause-specific mortality, according to a new study.
Intra-Articular NSAIDs Might Be Future OA Treatment
Are intra-articular non-steroidal anti-inflammatory drugs a viable option for treatment of osteoarthritis in adults?
Telehealth Rollback Puts Veterans Receiving Opioid Addiction Treatment at Risk
When the COVID-19 pandemic prompted federal policy changes increasing the use of telehealth delivery, one of those was the increased delivery of buprenorphine
OIG: Protocols to Help Prevent Suicides Not Always Followed at VA
Despite suicide prevention being a top priority at VA, clinicians are failing to consistently ask patients at risk for suicide about their access to guns.
Race Appeared to be Factor in Treatment of Veterans Hospitalized With COVID-19
Black veteran patients received different medical interventions than white patients when hospitalized with COVID-19 in VAMCs across the country, according to a new study.
VA Study: Paxlovid Can Reduce Risk of ‘Long COVID’ by About 25%
New research from the VA determined that Paxlovid can reduce the risk of symptoms of long COVID by about 25%.
VA Frailty Index Associated With Survival in AML Patients
Acute myeloid leukemia (AML) is a particularly aggressive blood cancer that is most successfully treated with intensive chemotherapy. As the average age at diagnosis is 68, patients diagnosed with the disease are often too frail to withstand potentially curative treatment with induction regimens.
New BTK Inhibitor Extends Progression-Free Survival in CLL
A late-breaking presentation at the 64th American Society of Hematology Annual Meeting in New Orleans on Dec. 13 demonstrated that zanubrutinib outperformed ibrutinib in terms of both objective response rate and progression-free survival for patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
Is It Time to Rethink Stem Cell Transplantation in Young Patients With MM?
BETHESDA, MD—Multiple myeloma (MM) is primarily a disease of the elderly, with an average age at diagnosis of 68. Still, adolescents and young adults (AYAs) do develop the blood disease and represent about 5% of all new cases. Because MM is so uncommon in younger age...
