Genetic Changes Increase Likelihood of Poor COVID-19 Outcomes in Chronic Lung Diseases; Environmental Exposures, Lifestyle Put Veterans at Higher Risk

Genetic Changes Increase Likelihood of Poor COVID-19 Outcomes in Chronic Lung Diseases; Environmental Exposures, Lifestyle Put Veterans at Higher Risk

Because they are molecularly susceptible to SARS-CoV-2, patients with chronic lung diseases appear to be primed for worse outcomes after infection, through the dysregulation of genes related to viral replication and the innate immune response in epithelial cells, and basal differences in inflammatory cell gene expression programs, according to a new study. The authors cautioned that patients with idiopathic pulmonary fibrosis are most at risk but the greater danger also affects those with chronic obstructive pulmonary disease and interstitial lung disease.

Altered Cholinergic Innervation in New Parkinson’s Patients

While evidence is strong that altered cholinergic innervation plays a key role in cognitive impairment in Parkinson’s disease (PD), at least in advanced stages, less is known about the relationship between cognitive impairment and cholinergic innervation early in the disease.

Milwaukee Nurse Identified Syringe Problem That Led to Recall

In August 2021, the medical device manufacturer Cardinal Health recalled approximately 267 million of their prefilled saline syringes. The syringes had been found to reintroduce air into the syringe after it had been expelled, which could have resulted in the injection of air into blood vessels, leading to serious injury or death.

Material things are delightful, but they’re not important

Material things are delightful, but they’re not important

When you are a billionaire like Sir Richard Branson, you tend to have a lot of stuff (I would assume). Furthermore, you are relieved of the pressure most people in the world feel to afford the necessities of life. While I agree with Branson’s thesis, I am not sure a person’s opinion regarding materialism is worth much when they command such overwhelming resources. As are most readers of this column, I am not a billionaire, although I recognize that my employment as a federal physician has supported my family far beyond basic necessities. Having traveled much of the world and witnessed first-hand the poverty that consumes much of the world’s population, I am keenly aware of how well we live in America.