Two drugs used in the treatment of several cancers have poorly understood drug-drug interactions that could have significant implications for patients.
Digging Deeper into Agent Orange, Genomic Alterations and Prostate Cancer
The defoliant known as Agent Orange has been linked to a wide range of malignancies since the conclusion of the Vietnam War, including prostate cancer.
Does Age, Treatment Selection Drive Differences in ALL Outcomes?
Acute lymphoblastic (or lymphocytic) leukemia (ALL) occurs more often in children than in adults and has much better outcomes in youngsters.
Surprise! Short-term ADT Might Benefit Cognition in Prostate Cancer Patients
In an unexpected turn of events, a team including investigators with the Naval Medical Center in Portsmouth, VA., found that adding short-term androgen deprivation therapy (STADT) to prostate bed salvage radiotherapy not only reduced progression in advanced prostate cancer but also improved patients’ mental processing speed.
Real-World Study Shows Veterans with NSCLC Benefit from Durvalumab
The continuing conundrum of clinical trials is how to assess their applicability to the patients actually seen in practice.
Obesity/Weight Gain Associated with MGUS Progression to Multiple Myeloma
Obesity ranks high in the list of risk factors for the development of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM).
Walter Reed Researchers Tackle Issues with Real-World Data on Multiple Myeloma
Real-world data holds the promise of enabling a better understanding of how medications work in the type of patients typically seen in clinics and hospitals.
Combination Therapy Outperforms ADT Alone in Metastatic Prostate Cancer
Studies have shown improved survival in patients who receive either docetaxel or androgen signaling agents (ASIs) such as abiraterone or enzalutamide in combination with androgen deprivation therapy.
VA’s Equal Access Care Mitigates Disparities in HCC Treatment, Outcomes
Rising rates of hepatocellular carcinoma (HCC) have focused attention on improving all aspects of the malignancy, from new methods of screening, earlier detection, more efficacious treatment, and extended survival. At the same time, the increased number of cases has made differences in access and outcomes more apparent.
Nivolumab Plus Cabozantinib Improves Health-related Quality of Life in RCC
At the 2023 American Society of Clinical Oncology (ASCO) annual meeting in Chicago a new analysis of data from the CheckMate 9ER trial was presented.
HER2 May Provide Therapeutic Target for Pancreatic Ductal Adenocarcinoma
PDAC accounts for 90% of all pancreatic cancers, which have an overall five-year survival rate of just 12%.
VA Demonstrates Success in Remote Treatment of Aggressive Cancers
Initially, the TeleOncology service managed oral therapies and watchful waiting and surveillance of veterans with cancer, but it has expanded to offer remote supervision for intravenous cancer treatments.
VA Study Shows Low Use of Primary Care for Reproductive Health Services
The integration of reproductive health services into primary care practices is increasingly recognized as critical to the advancement of patient-centered care and improving reproductive outcomes.
Quality Care Reduces Breast Cancer Survival Rate Disparities Based on Race
Though non-Hispanic Black women are more likely to have tumors at a higher grade and later stage and be diagnosed with triple-negative breast cancer
Frailty in Older Veterans Associated With Greater Suicide Attempt Risk
Veterans who are 65 and older and have symptoms of frailty are at increased risk of attempting suicide, and those with lower levels of frailty were found to have greater risk of suicide death, according to a new study.
Decline in Cerebral Cortical Thickness Linked to PD Cognitive Decline
What effect does reduced cerebral cortical thickness have in Parkinson’s disease (PD)?
Fewer Parkinson’s Motor Issues 11 Years After Deep Brain Stimulation
More than a decade after deep brain stimulation (DBS), early-stage Parkinson’s disease (PD) patients appeared to have fewer motor complications than those treated only with medications, according to a new study.
Cognitive Impairment Can Affect Parkinson’s Gait Rehab
What is the effect of baseline cognition on gait outcomes after a treadmill training program for Parkinson’s disease (PD) patients?
Cardiorespiratory Fitness Linked to Lower Abnormal Glucose Risk
Cardiorespiratory fitness (CRF) can be a good predictor of chronic disease. The problem is the difficulty and impracticability of routinely measuring that in primary care settings.
Cardiac Autonomic Neuropathy Linked to Stroke in T2D
What is the association between cardiac autonomic neuropathy (CAN) with incident stroke among diabetes mellitus patients?
Time in Range Beneficial in Patients With Individualized A1c
Individualizing hemoglobin A1c treatment goals in older adults is important to balance risks in benefits, according to a new study.
Deployed Servicemembers Had Lower Cancer Risks Than Those Who Weren’t
Despite concerns about exposure to hazardous material, military personnel who deployed to Southwest Asia actually had a lower risk of dying from cancer than their colleagues who were never deployed, according to a new study.
Elevated Preoperative Glucose Level Linked to Adverse Effects in Hernia Repair
An estimated 1 in 10 Americans and 1 in 4 veterans has diabetes, not only putting them at increased risk for problems such as heart and kidney disease, but also making them more prone to complications such as infection and bleeding following surgery.
VA’s Clinical Quality, Safety as Good or Better Than at Outside Care
A new review has determined that care provided in the VA healthcare system is consistently as good as or better than non-VA care in terms of clinical quality and safety.
VA Stops All EHR Rollouts; Says It Plans a ‘Reset’ of Program
VA has called a halt to all future deployments of its new electronic health record (EHR) system in order to prioritize fixing issues at the five sites where the system is already deployed.
Genetics Play a Role in Severe PTSD in Some Deployed Soldiers
The risk for specific soldiers to have severe post-traumatic stress disorder (PTSD) appears to far predate their deployment. In fact, some military personnel are born with it, according to a new study.
At All Levels, Chief Medical Office Scavella Focused on Best Care for Veterans
For a VA physician, it can be a challenge to figure out the best treatment plan for a patient and implement it, and the victory comes when the veteran’s health and quality of life is improved.
Promotion Delays Affecting Military Readiness But Senator Won’t Budge
Delays in promotions directly impacts military readiness, DoD officials have said. But there isn’t much they can do about it as long as Sen. Tommy Tuberville (R-AL) is blocking the expedited promotion of more than 150 military generals and flag officers
Mental Health of Veterans Before, During and After COVID-19 Pandemic
With work disruptions, social isolation and economic concerns, the pandemic understandably caused significant distress for many veterans.
VA Secretary McDonough: PACT Act Claims Numbers Still Too Small
VA has had more than a half-million claims filed under the new PACT Act legislation, which expands care and benefits for former servicemembers exposed to burn pits and other toxic substances during their service.
