Assessment of Sulphadoxine-pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Malawi

• Purpose: The purpose of this study is to determine the efficacy and effectiveness of sulphadoxine-pyrimethamine intermittent preventive treatment in pregnancy for reducing malaria-associated morbidity in pregnant women in Malawi.
• ClinicalTrials.gov Identifier: NCT01120145
• Sponsor: Centers for Disease Control and Prevention

Cell Lines From High-Risk Breast Tissue

• Objective: To establish a repository (facility in which tissue samples can be preserved and stored for many years) of cell lines from high-risk breast tissue to allow researchers to learn more about changes in breast cells that may cause them to develop into breast cancer.
• ClinicalTrials.gov Identifier: NCT00032201
• Sponsor: NCI

Docetaxel Alone or in Combination With Vaccine to Treat Breast Cancer

• Purpose: This study will test whether giving a combination of a vaccine together with docetaxel is more effective against breast cancer than docetaxel alone. The Food and Drug Administration has approved docetaxel to treat many cancers, including breast cancer.
• ClinicalTrials.gov Identifier: NCT00179309
• Sponsor: NCI

Increased Calorie Intake to Reverse Energy Deficiency in Exercising Women: Impact on Bone and Menstrual Cyclicity

• Purpose: The purpose of this study is to examine the effects of increased food intake on the menstrual cycle and bone health in physically active women who have irregular or absent menstrual cycles. This study will examine whether a 12-month period of increased food intake will cause menstrual cycles to resume and help bones get stronger.
• ClinicalTrials.gov Identifier: NCT00392873
• Sponsor: Penn State University
• Collaborator: DoD

Treatment of Menorrhagia in Women With Thrombocytopenia: Comparison of Platelet Transfusion Alone to Platelet Transfusion With Continuous Oral Contraceptive Pills

• Purpose: This study will explore the role of oral contraceptive pills in managing uterine bleeding in women who have low blood platelet counts as a result of aplastic anemia. Oral contraceptive pills have been shown to be effective in managing uterine bleeding in healthy women, but the effects have not been thoroughly studied in women who have low platelet counts. The purpose of the study is to determine whether oral contraceptive pills are a useful complement to platelet transfusions in women with aplastic anemia and uterine bleeding.
• ClinicalTrials.gov Identifier: NCT00556400
• Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development

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