Advertisement
Departments | Specialty Focus | Non-Clinical Topics | News | Special Issues | e-Newsletter | Education | Archive | Site Search

Treating a Million Diabetes Patients, VA Stays at Cutting Edge

With responsibility for treating diabetes in more than a million veterans in its primary-care population, VA is at the leading edge of care for the metabolic disease.

For example, an article this spring in the Annals of Internal Medicine focused on an ongoing debate in medical circles: Whether a “one-size-fits-all” target level for Hemoglobin A1c in diabetes is the best approach, or whether an individualized approach is more appropriate.

The authors supported the latter approach — one that VA has long endorsed.

Dr. Leonard Pogach, VA Diabetes Program Director (left), reviews Clinical Practice Guideline Criteria with staff. Photo from VA website.

“The VA/DoD Clinical Practice Guidelines for Diabetes have for more than 10 years included stratified targets based on life expectancy and co-comorbidities,” wrote a group of authors responding to the study on behalf of the VA/DoD Diabetes Practice Guidelines Working Group. “Moreover, all of the trials referred to in their article were utilized in updating the guidelines which were released in August, 2010.”

Unlike the more specific glycemic targets recommended by the authors in the Annals article, however, the VA/DoD Diabetes Practice Guidelines Working Group, the response noted, “Recommends target ranges rather than single targets — from <7%, 7-8%, and 8-9%.” (Please see the table on final page.)

“What I can tell you is that, over time, many of the VA-DoD recommendations that seemed controversial at the time because they did not agree with professional society guidelines now seem to be good science —that is, our experts were properly cautious,” said Leonard M. Pogach, MD, MBA, the Veterans Health Administration national program director for endocrinology and diabetes, Office of Specialty Care, Patient Care Services, chair of the VA/DoD Diabetes Working Group, director of CHeKM, and professor of Medicine, UMDNJ-New Jersey Medical School. Pogach also noted that VA removed Avandia from its formulary in late 2007, about three years before the FDA took action, adding, “So you might want to categorize our approach as ‘safety first.’”

VA First With Performance Measures

VA implemented the first national performance measures for diabetes in 1996; it was the first national delivery system to standardize Hemoglobin A1c (1999); and started a tele-retinopathy demonstration project in 1999.

 “Diabetes was also one of the original Quality Improvement Research Enhancement Initiatives in 1998,” Pogach recounted. All of this was well prior to the 2000 Institute of Medicine report that first mentioned a possible link between Agent Orange and type 2 diabetes. “It was already recognized that diabetes was a major health issue for veterans,” Pogach notes. Between 20% and 25% of the veterans in the VHA primary care population (over 5 million in all) have diabetes, according to the Working Group.

VA added type 2 diabetes to the list of "presumptive diseases associated with herbicide exposure" in 2000, following a report from the National Academy of Sciences that found "limited/suggestive" evidence of an association between the chemicals used in herbicides during the Vietnam War, such as Agent Orange, and type 2 diabetes.


Comments (2)

Darin Olson
Said this on 12-1-2011 At 06:03 pm

It is laudable and appropriate for the VA to have been on the vanguard of individualizing treatment goals for patients. However, some of the recommendations may benefit from clarification or may not be correct. 

For example, there may not to be a role to establish a higher goal range of 8-9%, in any setting.  It would seem more prudent to use A1c as a monitoring tool without any goal once prevention of microvasclar complications is no longer necessary.  It would be better to state treatment goals of avoiding both hypoglycemia and symptomatic hyperglycemia at those times.  A1c might alert the provider to higher risk of hypoglycemia or hyperglycemia, but no longer be a goal of therapy. 

It also seems inaccurate to raise the goal A1c in most patients with established complications. It may be greater benefit to reduce the rate of progression of established complications to delay severe disability from blindness or dialysis, and this would recommend improving A1c from whatever level that led to he onset of the microvascular complication. 

It is harder to codify this into a simple table, but to paraphrase H.L Mencken: there may be a simple, elegant, attractive solution, but it is often wrong.

Brad Solie
Said this on 12-12-2011 At 11:18 am

The 8-9% A1c range is used because that was the target for standard control in the VA Diabetes Trial (VADT).

Post a Comment (showhide)
* Your Name:
* Your Email:
(not publicly displayed)
Reply Notification:
Approval Notification:
Website:
* Security Image:
Security Image Generate new
Copy the numbers and letters from the security image:
* Message:

Advertisement